Maine coon: inherited diseases and health

Updated 2026-09-30 · 3 sources

Based on: OMIA (University of Sydney), Science for Animal Welfare (UFAW), Wikidata

Breed health

The inherited conditions below have been documented in this breed in published research. That does not mean your cat has them or will get them – but it helps to know the names when you talk to a breeder or a vet.

Conditions this breed is prone to

Veterinary charities list this breed as more likely than others to get these conditions. Read the signs and what to do:

Inherited conditions documented in the breed

Conditions documented: 20

A gene variant is known for 16 of the conditions below, so a DNA test may exist. Ask your vet or the breed club.

ConditionBody systemInheritanceGene variant known
Auditory-pigmentary syndrome, PAX3-related[1]PigmentationAutosomal dominantYes
Cardiomyopathy, hypertrophic[1]Cardiovascular system––
Cardiomyopathy, hypertrophic, MYBPC3-related, autosomal recessive[1]Cardiovascular systemAutosomal recessiveYes
Cardiomyopathy, hypertrophic, TNNT2-related[1]Cardiovascular systemProbably autosomal recessiveYes
Cataract, generic[1]Vision / eye––
classical Ehlers-Danlos syndrome (cEDS), COL5A1-related[1]Integument (skin)Autosomal dominantYes
Cystinuria, type B[1]Renal / urinary system–Yes
Factor XI deficiency[1]Haematopoietic systemAutosomal recessiveYes
Factor XII deficiency[1]Haematopoietic systemAutosomal recessiveYes
Fibrodysplasia ossificans[1]MuscleAutosomal dominantYes
Hypertrophic Cardiomyopathy[2]–––
Multidrug resistance 1, ABCB1-related[1]Homeostasis / metabolism–Yes
Muscular dystrophy, Becker type[1]MuscleX-linked recessiveYes
Muscular dystrophy, congenital merosin-deficient[1]MuscleAutosomalNo
Muscular dystrophy, Duchenne type[1]MuscleX-linkedYes
Polycystic kidney disease[1]Renal / urinary systemAutosomal dominant + recessive lethalYes
Polydactyly[1]Skeleton (incl. short stature & teeth)Autosomal dominant with incomplete penetranceYes
Pyruvate kinase deficiency of erythrocyte[1]Homeostasis / metabolismAutosomal recessiveYes
Retinal degeneration II[1]Vision / eyeAutosomal recessiveYes
Spinal muscular atrophy, LIX1-related[1]Nervous systemAutosomal recessiveYes

What this list means

  • “Documented in the breed” means at least one published case or study – it says nothing about how common the condition is.
  • Many of these conditions are rare. A responsible breeder can tell you which health tests the parents have had.
  • Where the gene variant is known, a DNA test may exist – ask your vet or the breed club.
  • If your pet shows signs of illness, contact your vet. This page cannot tell you whether your pet is ill.

About the breed

Origin
United States
Weight
4.5–11 kg
[3]
If your pet is struggling to breathe, has collapsed, is having a seizure or can't stand up: go to the nearest vet now.

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Sources

  1. OMIA (University of Sydney)
  2. Science for Animal Welfare (UFAW)
  3. Wikidata

How this page was made: the list is taken directly from the sources below; nothing on it was written by AI. Names of conditions may be machine-translated. It is information, not a diagnosis. How we write our pages

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