English Mastiff: inherited diseases and health
The inherited conditions below have been documented in this breed in published research. That does not mean your dog has them or will get them – but it helps to know the names when you talk to a breeder or a vet.
Conditions this breed is prone to
Veterinary charities list this breed as more likely than others to get these conditions. Read the signs and what to do:
Cherry EyeInherited conditions documented in the breed
Conditions documented: 7
A gene variant is known for 3 of the conditions below, so a DNA test may exist. Ask your vet or the breed club.
| Condition | Body system | Inheritance | Gene variant known |
|---|---|---|---|
| Cervical vertebral compressive myelopathy[1] | Skeleton (incl. short stature & teeth) | – | – |
| Cystinuria, type III[1] | Renal / urinary system | – | No |
| Degenerative myelopathy[1] | Nervous system | Autosomal recessive | Yes |
| Multifocal retinopathy 1[1] | Vision / eye | Autosomal recessive | Yes |
| Osteogenesis imperfecta, generic[1] | Skeleton (incl. short stature & teeth) | Autosomal dominant | No |
| Retinal atrophy, progressive, autosomal dominant, RHO-related[1] | Vision / eye | Autosomal dominant | Yes |
| Retinal dysplasia[1] | Vision / eye | – | – |
What this list means
- “Documented in the breed” means at least one published case or study – it says nothing about how common the condition is.
- Many of these conditions are rare. A responsible breeder can tell you which health tests the parents have had.
- Where the gene variant is known, a DNA test may exist – ask your vet or the breed club.
- If your pet shows signs of illness, contact your vet. This page cannot tell you whether your pet is ill.
About the breed
- Origin
- England
- FCI number
- 264
Not sure how serious it is?
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Sources
How this page was made: the list is taken directly from the sources below; nothing on it was written by AI. Names of conditions may be machine-translated. It is information, not a diagnosis. How we write our pages