My dog ate naproxen – what should I do?

Updated 2026-09-30 · 2 sources

Based on: Pet Poison Helpline, Outcomes of 434 dogs with NSAID toxicosis, J Vet Intern Med 2023

Call a vet now

Call your vet or the nearest emergency vet right now. Naproxen is very poisonous to dogs, and as little as one 220 mg tablet can cause very serious symptoms, even death, even in a large dog.

What to do right now

  1. Call your vet or the nearest emergency vet.
  2. Note what was eaten, how much, and when.
  3. Bring the packaging.
  4. Keep your dog calm.
  5. Remove any naproxen left within reach.

Don't

  • Do not make your dog vomit unless a vet tells you to.
  • Do not give any human medicine.

Why it can be dangerous

Naproxen is very poisonous to dogs.[1] As little as one 220 mg tablet can cause very serious symptoms, even death, even in a large dog.[1] One study defined naproxen doses above 5 mg/kg as gastrointestinal toxicity, above 25 mg/kg as kidney toxicity, and above 50 mg/kg as central nervous system toxicity.[2]

Signs to watch for

  • vomiting
  • diarrhea
  • lethargy
  • seizures
  • weakness
  • kidney failure
  • anemia
  • bleeding

Where it is found

  • over-the-counter medicines
  • prescription medicines

What the experts say

“As little as one 220mg tablet can cause very serious symptoms (even death), even in a large dog.”

— Pet Poison Helpline [1]
If your pet is struggling to breathe, has collapsed, is having a seizure or can't stand up: go to the nearest vet now.

Not sure how serious it is?

OkPaw asks a few quick questions about your pet and tells you in 30 seconds whether it can wait. Free on Google Play for Android.

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Common questions

How much naproxen can be dangerous?

As little as one 220 mg tablet can cause very serious symptoms, even death, even in a large dog.[1]

What can naproxen do to a dog?

Naproxen is very poisonous to dogs.[1]

What should I do now?

Call your vet or the nearest emergency vet right now; note what, how much, and when, and bring the packaging.

Sources

  1. Pet Poison Helpline
  2. Outcomes of 434 dogs with NSAID toxicosis, J Vet Intern Med 2023

How this page was made: written with the help of AI from the sources below, then checked claim by claim against those sources. Urgency levels follow OkPaw’s fixed safety rules. It is guidance, not a diagnosis. How we write our pages

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