My cat ate antihistamines – what should I do?

Updated 2026-09-30 · 1 sources

Based on: Pet Poison Helpline

Call a vet today

Call your vet today for advice – don't wait until signs appear. An accidental overdose can cause depression, hyperstimulation, or gastrointestinal distress.

What to do right now

  1. Call your vet or the nearest emergency vet.
  2. Note what was eaten, how much and when.
  3. Bring the packaging.
  4. Keep your cat calm.
  5. Remove what is left.

Don't

  • Do not make your cat vomit unless a vet tells you to.
  • Do not give any human medicine.

Why it can be dangerous

An accidental antihistamine overdose in cats can cause neurological or cardiovascular depression or hyperstimulation.[1] An accidental antihistamine overdose can also cause gastrointestinal distress.[1]

Signs to watch for

  • Depression

Where it is found

  • Human medicine
  • Veterinary medicine
If your pet is struggling to breathe, has collapsed, is having a seizure or can't stand up: go to the nearest vet now.

Not sure how serious it is?

OkPaw asks a few quick questions about your pet and tells you in 30 seconds whether it can wait. Free on Google Play for Android.

Get it on Google Play

OkPaw is on Android now – an iPhone version is on its way.

Common questions

How much antihistamine is dangerous?

An accidental overdose can cause neurological or cardiovascular depression or hyperstimulation and gastrointestinal distress.[1]

What signs should I watch for?

Depression can occur.[1]

Sources

  1. Pet Poison Helpline

How this page was made: written with the help of AI from the sources below, then checked claim by claim against those sources. Urgency levels follow OkPaw’s fixed safety rules. It is guidance, not a diagnosis. How we write our pages

The same page for dogs →

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